Advancements in the Association between a Body Shape Index and Atherosclerosis
摘要: 体型指数(ABSI)是基于身高、体重、腰围等测量指标通过特定算法衍生的新型人体测量学指标。随着超重和肥胖人群的日益增多,腹型肥胖对于心血管事件发生和死亡的预测作用更强。肥胖通过产生炎症因子,诱发慢性炎症反应、胰岛素抵抗、代谢紊乱和氧化应激途径等导致动脉硬化、高血压、冠心病等心血管疾病的发病甚至死亡。ABSI与腹型肥胖相关性较好,在部分人群中可以预测动脉硬化,但同时也受到人群特征的影响。例如,不同地区、性别和年龄的人群中,ABSI与动脉硬化之间的相关性存在差异。明确ABSI与动脉硬化的关系,对早期发现动脉硬化的高危人群和合理防治心血管疾病有重要意义。
Abstract: A body shape index (ABSI) is a novel anthropometric index derived by specific algorithms based on measurements of height,weight,and waist circumference. Central obesity has become more important for predicting the occurrence and mortality of cardiovascular events with the increasing number of overweight and obese people. Obesity contributes to the development of cardiovascular diseases such as atherosclerosis,hypertension,coronary heart disease and even death by stimulating the production of inflammatory factors that induce chronic inflammatory responses,insulin resistance,metabolic disorders and oxidative stress pathways. ABSI is strongly related to abdominal obesity and can predict atherosclerosis in some populations,but it is also affected by population characteristics,such as the difference in the correlation between ABSI and atherosclerosis in populations of different regions,genders and ages. It is of great significance for early identification of high risk populations and rational prevention and treatment of cardiovascular diseases to clarify the relationship between ABSI and atherosclerosis.
[V1] | 2023-11-16 10:37:29 | ChinaXiv:202311.00143V1 | 下载全文 |
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